Handy keyboard shortcuts

Windows key:

• Windows + e - Open file explorer
• Windows + d - Show desktop or restore all windows
• Windows + r - Open "run" window
• Windows + f - Open search

Tab key:

• Tab - Move focus to the next item
• SHIFT + Tab - Move focus to the previous item
• CTRL + Tab - Switch between tabs
• ALT + Tab - Switch between windows

CTRL key:

• CTRL + c - Copy
• CTRL + x - Cut
• CTRL + v - Paste
• CTRL + z - Undo
• CTRL + b - Enable/disable Bold font
• CTRL + u - Enable/remove Underline
• CTRL + i - Enable/remove Italic
• CTRL + F4 - Close current tab
• CTRL + t - New browser Tab (works only within the browser)
• CTRL + n - New browser wiNdow (works only within the browser)

Function keys:

• F1 - Help
• F2 - Rename file
• F3 - Search text forward
• SHIFT + F3 - Search text backward
• ALT + F4 - Close window
• F5 - Refresh

Deleting:

• Del - Move item to Recycle bin
• SHIFT + Del - Delete item forever (don't move to Recycle bin)

Others:

• Open task manager: CTRL + SHIFT + ESC
• Display "Open with...": SHIFT + Right click
• Open properties: ALT + Enter
• Display browser history: CTRL + h (works only within the browser)
• Space bar (on dialogs) - Execute the current button action, toggle check boxes.

Menu manipulation:

• Create a New folder - ALT + f , w, f  (in the explorer window)
• Save file - ALT + f, s  (sometimes - CTRL + s)
• Save file as - ALT + f, a
• Find text - CTRL + f
• Replace text - CTRL + h (sometimes - CTRL +  r)
• Close - ALT + f, x

You can find the complete list here:
http://support.microsoft.com/kb/126449

Note: In any software press the ALT key to use menu shortcuts - The shortcut keys have an underscore.